Secondly, this question is not significantly different than the last one? What's with the sads? Did Debbie Downer write this prompt list? Am I just supposed to be heaping sorrows upon you, Dear Readers? Again, who knows.
So, okay, "The Saddest Scene" in all of mangadom is...
|WAAAAAAH! So sad!|
(No really, it is very sad.)
This scene from Loveless (chapter 26) kills me. Every single time.